How do new chromosomes evolve? A new paper from the lab describes an incredible new karyotype in which all females of a D. melanogaster strain carry a Y chromosome, and discovers that it’s driven by loss of rDNA from the X. Check it out!
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How do germline cells retain their immortality, especially since so many necessary cellular components are prone to loss? A new paper from our lab identifies a novel gene, Indra, as necessary for maintaining the appropriate copy number of rDNA repeats in germline stem cells, allowing them to give rise to the next generation! Check it …
In any context, introns and repetitive satellite DNA have often been seen as mere “genomic junk,” but recent work suggests that both – including satellites contained with introns – have necessary functions. Check out a review of this from the lab here.
Germline fate is more plastic than you might think – it can arise (or disappear) in many different species in very different ways. Check out a review on this topic from the lab here.
A new review from the Yamashita lab explores how centrosome asymmetry could underlie asymmetric cell divisions. Check it out here!