How do new chromosomes evolve? A new paper from the lab describes an incredible new karyotype in which all females of a D. melanogaster strain carry a Y chromosome, and discovers that it’s driven by loss of rDNA from the X. Check it out!
How do germline cells retain their immortality, especially since so many necessary cellular components are prone to loss? A new paper from our lab identifies a novel gene, Indra, as necessary for maintaining the appropriate copy number of rDNA repeats in germline stem cells, allowing them to give rise to the next generation! Check it …
In any context, introns and repetitive satellite DNA have often been seen as mere “genomic junk,” but recent work suggests that both – including satellites contained with introns – have necessary functions. Check out a review of this from the lab here.
Germline fate is more plastic than you might think – it can arise (or disappear) in many different species in very different ways. Check out a review on this topic from the lab here.
A new review from the Yamashita lab explores how centrosome asymmetry could underlie asymmetric cell divisions. Check it out here!